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'CANNABIS' MAY HELP MENTALLY ILL
Chemicals found in cannabis could be used to relieve symptoms of severe
mental illnesses such as bipolar disorder, researchers have claimed.
The drug itself has previously been linked to an increased risk of
developing such conditions.
But a University of Newcastle team, writing in the Journal of
Psychopharmacology said cannabinoids might help.
Mental health campaigners called for further work to confirm this.
For most people with severe mental illness, raw cannabis remains a risky
substance Jane Harris, Rethink
The Newcastle researchers said anecdotal reports from people with mental
illnesses suggested cannabis could alleviate symptoms.
But they warned smoking the drug had been shown to cause long-term damage
to mental health, and to increase the risk of mental illness in those who
were already genetically susceptible.
Highs and Lows
Scientists have been trying to find ways of harnessing the beneficial
aspects of the drug without exposing people to the harmful ones.
The Newcastle team reviewed research carried out into the properties of
cannabis.
They found evidence that two chemicals in cannabis could aid people with
mental illness; THC ( tetrahydrocannabinol ) and CBD ( cannabidiol ).
THC helps give the 'high' associated with cannabis use, while CBD has been
found to have calming properties.
Combined, they could help people with bi-polar disorder avoid the manic
highs and depressed lows of their condition.
The Newcastle team say trials should now be carried out to see if the
combination of chemicals does help people.
They are hoping to use a mouth spray created by GW Pharmaceuticals
containing THC and CBD, which has been licensed for use for pain relief in
Canada, once it is licensed in the UK.
The company is already involved in research looking at whether cannabinoids
can relive pain symptoms for people with disease such as multiple sclerosis.
Medicinal Use
Heather Ashton, professor of clinical psychopharmacology, who led the
study, told the BBC News website: "If you use this mixture in the right
dose and the right proportions, you might very well be able to help people
with bipolar disorder, whatever way they are veering.
"We think it might be useful to patients to try, as an add-on not as a
single drug, a known mixture of certain cannabinoids."
She added: "People who take cannabis for relief of these symptoms do not
need the heavy doses that recreational users take."
But Professor Ashton stressed: "We all agree that smoking cannabis,
especially when young, in large quantities is associated with mental illness.
"That is quite different from using it medicinally."
Jane Harris, campaigns officer at the mental health charity Rethink said:
"Cannabinoids are an exciting new area for medical research, but it is
important to recognise that there are over 60 active ingredients in
cannabis - the two mentioned in this study may help in the treatment of
bipolar disorder when taken in controlled doses.
"But for most people with severe mental illness, raw cannabis remains a
risky substance.
"All medical research needs to be checked before it would make a difference
to the hundreds of thousands of people living with severe mental illness in
the UK."
In January this year, the government announced a review of all academic and
clinical studies linking cannabis use to mental health problems.
